FEATURES

FAMILY

DESCRIPTION

Also known as DYHC_YEAST, DYN1, DHC1. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required to maintain uniform nuclear distribution in hyphae. May play an important role in the proper orientation of the mitotic spindle into the budding daughter cell yeast. Probably required for normal progression of the cell cycle. The dynein complex consists of at least two heavy chains and a number of intermediate and light chains. Interacts with DYN3.

EXTERNAL LINKS

uniprot
enzyme classification

DYN1

Mutations

Mutation(s) distribution

Mutations table