FEATURES

FAMILY

DESCRIPTION

Also known as MIC60_YEAST, MIC60, AIM28, FCJ1, FMP13. Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway. Component of the mitochondrial contact site and cristae organizing system (MICOS) complex, composed of at least MIC10, MIC12, MIC19, MIC26, MIC27 and MIC60. This complex was also known under the names MINOS or MitOS complex. Interacts with TOM22 and TOM40 in a MICOS-independent manner, resulting in coupling with the outer membrane. Interacts with MIA40, OM45 and POR1.

Also known as MIC60_YEAST, MIC60, AIM28, FCJ1, FMP13. Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of cr ...

MIC60

Structural Ligandability

Domains Chains

Distribution