FEATURES

FAMILY

DESCRIPTION

Also known as GEF1_YEAST, GEF1, CLCY1. Anion/proton exchange transporter involved in iron and copper cation homeostasis. Involved in intracellular iron metabolism during growth on fermentable and non fermentable carbon sources. Required for proper copper-loading and maturation of multicopper oxidase FET3. Important for adjusting intracellular compartment pH to more alkaline pH under iron limitation. May also transport chloride ions through the plasma membrane. Homodimer (By similarity). Interacts with GET3.

EXTERNAL LINKS

uniprot
enzyme classification

GEF1

Anion/proton exchange transporter GEF1

GEF1

Structural Ligandability

Domains Chains

Distribution