FEATURES

FAMILY

DESCRIPTION

Also known as SRP14_HUMAN, SRP14. Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. Signal recognition particle consists of a 7S RNA molecule of 300 nucleotides and six protein subunits: SRP72, SRP68, SRP54, SRP19, SRP14 and SRP9.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SRP14

Signal recognition particle 14 kDa protein

Mutations

Mutation(s) distribution

Mutations table

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