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FEATURES

FAMILY

DESCRIPTION

Also known as O17C_CONMA, O17C. Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav). This toxin preferentially blocks P/Q-type calcium channels (Cav2.1/CACNA1A) (IC(50)=0.60 nM) (PubMed:1352986, PubMed:10938268). Shows also an inhibition on Cav2.2/CACNA1A channels (IC(50)=7.0 nM) (PubMed:10938268).

Also known as O17C_CONMA, O17C. Omega-conotoxins act at presynaptic membranes, they bind and block voltage-gated calcium channels (Cav). This toxin preferentially blocks P/Q-type calcium channels (C ...

EXTERNAL LINKS

uniprot
enzyme classification

O17C

Omega-conotoxin MVIIC

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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