FEATURES

FAMILY

DESCRIPTION

Also known as TAUD_ECOLI, tauD, ssiD, yaiG. Catalyzes the alpha-ketoglutarate-dependent hydroxylation of taurine yielding sulfite and aminoacetaldehyde after decomposition of an unstable intermediate (PubMed:9287300). Is required for the utilization of taurine (2-aminoethanesulfonate) as an alternative sulfur source for growth in the absence of sulfate (PubMed:8808933). To a lesser extent, pentanesulfonate, 3-(N-morpholino)propanesulfonate and 1, 3-dioxo-2-isoindolineethanesulfonate are also desulfonated by this enzyme in vitro; however, desulfonation by TauD of organosulfonates other than taurine seem to be of little or no importance for sulfur metabolism in vivo (PubMed:9287300). Homodimer (PubMed:11955067, PubMed:12741810, PubMed:9287300). Was later shown to be a homotetramer arranged as a dimer of two dimers (PubMed:22221834).

EXTERNAL LINKS

tauD

Mutations

Mutation(s) distribution

Mutations table