FEATURES

FAMILY

DESCRIPTION

Also known as YNG2_YEAST, YNG2, EAF4, NBN1. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in cell cycle progression and meiosis. Interacts with H3K4me3 and to a lesser extent with H3K4me2. Component of the NuA4 histone acetyltransferase complex composed of at least ACT1, ARP4, YAF9, VID21, SWC4, EAF3, EAF5, EAF6, EAF7, EPL1, ESA1, TRA1 and YNG2.

EXTERNAL LINKS

uniprot
enzyme classification

YNG2

Chromatin modification-related protein YNG2

Mutations

Mutation(s) distribution

Mutations table

Search Mutation