FEATURES

FAMILY

DESCRIPTION

Also known as RIO2_YEAST, RIO2. Required for the final endonucleolytic cleavage of 20S pre-rRNA at site D in the cytoplasm, converting it into the mature 18S rRNA. Involved in normal export of the pre-40S particles from the nucleus to the cytoplasm. No longer associates with pre-40S subunits in RPS19 disruptions, suggesting it acts after the ribosomal protein in 18S rRNA maturation. Component of a late pre-40S ribosomal particle, composed of the 40S ribosomal proteins and the non-ribosomal factors DIM1, DIM2, ENP1, HRR25, LTV1, NOB1, RIO2 and TSR1.

EXTERNAL LINKS

uniprot
enzyme classification

RIO2

Serine/threonine-protein kinase RIO2

RIO2

Molecular Synopsis