FEATURES

FAMILY

DESCRIPTION

Also known as RFC3_HUMAN, RFC3. The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. Heterotetramer of subunits RFC2, RFC3, RFC4 and RFC5 that can form a complex either with RFC1 or with RAD17. The former interacts with PCNA in the presence of ATP, while the latter has ATPase activity but is not stimulated by PCNA.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RFC3

Replication factor C subunit 3

RFC3

Molecular Synopsis