FEATURES

DESCRIPTION

Also known as CBF3B_YEAST, CEP3, CBF3, CBF3B, CSL1. Acts as a component of the centromere DNA-binding protein complex CBF3, which is essential for chromosome segregation and movement of centromeres along microtubules. CBF3 is required for the recruitment of other kinetochore complexes to CEN DNA. It plays a role in the attachment of chromosomes to the spindle and binds selectively to a highly conserved DNA sequence called CDEIII, found in centromers and in several promoters. Component of the CBF3 copmplex, which is formed of CBF3A/CBF2, CBF3B/CEP3, CBF3C/CTF13 and CBF3D.

Also known as CBF3B_YEAST, CEP3, CBF3, CBF3B, CSL1. Acts as a component of the centromere DNA-binding protein complex CBF3, which is essential for chromosome segregation and movement of centromer ...

EXTERNAL LINKS

uniprot
enzyme classification

CEP3

Mutations

Mutation(s) distribution

Mutations table