FEATURES

FAMILY

purine/pyrimidine phosphoribosyltransferase family

DESCRIPTION

Also known as PYRR_BACCL, pyrR. Regulates transcriptional attenuation of the pyrimidine nucleotide (pyr) operon by binding in a uridine-dependent manner to specific sites on pyr mRNA. This disrupts an antiterminator hairpin in the RNA and favors formation of a downstream transcription terminator, leading to a reduced expression of downstream genes (Probable)., Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant. Homodimer and homohexamer; in equilibrium.

EXTERNAL LINKS

uniprot
enzyme classification

pyrR

Mutations

Mutation(s) distribution

Mutations table