FEATURES

FAMILY

DESCRIPTION

Also known as DPOLX_ASFB7, O174L. Error-prone polymerase lacking a proofreading 3'-5' exonuclease which plays a role in viral DNA repair. Specifically binds intermediates in the single-nucleotide base-excision repair process. Also catalyzes DNA polymerization with low nucleotide-insertion fidelity. Together with the viral DNA ligase, fills the single nucleotide gaps generated by the AP endonuclease.

EXTERNAL LINKS

uniprot
enzyme classification

O174L

Repair DNA polymerase X

O174L

Molecular Synopsis