FEATURES

FAMILY

DESCRIPTION

Also known as RAD52_HUMAN, RAD52. Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase. The full-length protein forms heptameric rings (PubMed:12191481). Interacts with ABL1 (PubMed:12379650). Interacts with RPA2; the interaction is direct and associates RAD52 with the RPA complex (PubMed:8702565). Interacts with RAD51AP1 (PubMed:31400850).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RAD52

DNA repair protein RAD52 homolog

RAD52

Molecular Synopsis