FEATURES

DESCRIPTION

Also known as MAGA1_HUMAN, MAGEA1, MAGE1, MAGE1A. May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. Interacts with SNW1 and HDCA1.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MAGEA1

Melanoma-associated antigen 1

MAGEA1

Molecular Synopsis