FEATURES

FAMILY

DESCRIPTION

Also known as CPOB_ECOLI, cpoB, ybgF. Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division. Promotes physical and functional coordination of the PBP1B-LpoB and Tol machines, and regulates PBP1B activity in response to Tol energy state. Homotrimer (PubMed:20455268, PubMed:20816983). Interacts directly with the central domain of TolA and with PBP1B (PubMed:11994151, PubMed:20816983, PubMed:25951518). Binding to TolA disrupts the homotrimer to form a YbgF/TolA heterodimer with weak affinity (PubMed:20816983). Forms a quaternary complex with PBP1B-LpoB and TolA (PubMed:25951518).

EXTERNAL LINKS

uniprot
enzyme classification

cpoB

Mutations

Mutation(s) distribution

Mutations table