FEATURES

FAMILY

Classic translation factor GTPase family

DESCRIPTION

Also known as IF2M_HUMAN, MTIF2. One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex. Monomer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

MTIF2

Translation initiation factor IF-2, mitochondrial

MTIF2

Molecular Synopsis