FEATURES

FAMILY

DESCRIPTION

Also known as CDT1_YEAST, TAH11, CDT1, SID2. DNA replication licensing factor, required for pre-replication complex assembly. Faithful duplication of the genetic material requires 'once per cell cycle' DNA replication initiation and elongation. Central to this control is the tightly regulated formation of prereplicative complexes (preRCs) at future origins of DNA replication. Required for the recruitment of the MCM2-7 helicase complex to the replication origins. Associates with the MCM2-7 complex. Interacts with MCM2, ORC1, ORC2 and ORC6.

EXTERNAL LINKS

uniprot
enzyme classification

TAH11

Cell division cycle protein CDT1

TAH11

Molecular Synopsis