FEATURES

FAMILY

DESCRIPTION

Also known as AL7A1_HUMAN, ALDH7A1, ATQ1. Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism. Homotetramer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

ALDH7A1

Alpha-aminoadipic semialdehyde dehydrogenase

Mutations

Mutation(s) distribution

Mutations table

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