FEATURES

FAMILY

DESCRIPTION

Also known as ST1A2_HUMAN, SULT1A2, STP2. Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of catecholamines, phenolic drugs and neurotransmitters. Is also responsible for the sulfonation and activation of minoxidil. Mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and could so participate as modulating factor of cancer risk. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

SULT1A2

Sulfotransferase 1A2

SULT1A2

Molecular Synopsis