No data available

FEATURES

FAMILY

peptidase S1 family

DESCRIPTION

Also known as GRAM_HUMAN, GZMM, MET1. Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.

Also known as GRAM_HUMAN, GZMM, MET1. Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha-tubulins and the apoptosis inhibitor BIRC5/ ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

GZMM

Granzyme M

Molecular Synopsis

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