FEATURES

FAMILY

DESCRIPTION

Also known as CLCN3_HUMAN, CLCN3. Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons (By similarity). The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons (PubMed:29845874). The presence of conserved gating glutamate residues is typical for family members that function as antiporters (PubMed:29845874)., Strongly outwardly rectifying, electrogenic H(+)/Cl(-)exchanger which mediates the exchange of chloride ions against protons. Monomer and homodimer (By similarity). Forms heterodimers with CLCN4 (By similarity).

EXTERNAL LINKS

CLCN3

H(+)/Cl(-) exchange transporter 3

CLCN3

Molecular Synopsis