FEATURES

DESCRIPTION

Also known as MLC1_YEAST, MLC1. Essential light chain for the class II conventional myosin MYO1. Acts also as light chain for the class V unconventional myosin MYO2 and for IQG1. Involved in the assembly of the contractile actomyosin ring at the bud neck during cytokinesis by recruiting IQG1 to the bud neck. Also required for chitin and MYO2-dependent secretory vesicle deposition to the center of the bud neck for septum formation. May stabilize MYO2 by binding to its IQ domains. Its major function is probably not to regulate MYO1 activity, but rather to coordinate actin ring formation and targeted membrane deposition during cytokinesis via its interactions with MYO1, IQG1 and MYO2. Interacts with MYO1, MYO2 and IQG1 by binding to their IQ domains. Interacts with SEC4.

EXTERNAL LINKS

MLC1

Mutations

Mutation(s) distribution

Mutations table