FEATURES

DESCRIPTION

Also known as MTP_HUMAN, MTTP, MTP. Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces (PubMed:23475612, PubMed:8939939, PubMed:26224785, PubMed:25108285, PubMed:22236406, PubMed:16478722, PubMed:15897609, PubMed:8876250). Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B (PubMed:23475612, PubMed:8939939, PubMed:26224785, PubMed:8876250, PubMed:16478722). May be involved in regulating cholesteryl ester biosynthesis in cells that produce lipoproteins (By similarity). Heterodimer; heterodimerizes with the protein disulfide isomerase (P4HB/PDI) (PubMed:23475612, PubMed:26224785, PubMed:25108285, PubMed:16478722). Interacts with APOB (PubMed:26224785, PubMed:25108285, PubMed:27206948). Interacts with PRAP1 (By similarity).

Also known as MTP_HUMAN, MTTP, MTP. Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces (PubMed:23475612, PubMed:8939939, PubMed:26224785, ...

EXTERNAL LINKS

MTTP

Microsomal triglyceride transfer protein large subunit

Mutations

Mutation(s) distribution

Mutations table

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