FEATURES

FAMILY

ligand-gated ion channel (TC 1.A.9) family

DESCRIPTION

Also known as GBRR1_MOUSE, Gabrr1. GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission (By similarity). Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho. Interacts with SQSTM1 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification

Gabrr1

Gamma-aminobutyric acid receptor subunit rho-1

Gabrr1

Structural Ligandability

Domains Chains

Distribution