FEATURES

FAMILY

D-isomer specific 2-hydroxyacid dehydrogenase family

DESCRIPTION

Also known as CTBP2_HUMAN, CTBP2. Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity)., Isoform 2 probably acts as a scaffold for specialized synapses. Can form homodimers or heterodimers of CTBP1 and CTBP2. Interacts with HIPK2 and ZNF217. Interacts with PRDM16; represses white adipose tissue (WAT)-specific genes expression (By similarity). Interacts with PNN, NRIP1 and WIZ. Interacts with MCRIP1 (PubMed:25728771).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

CTBP2

C-terminal-binding protein 2

CTBP2

Molecular Synopsis