FEATURES

DESCRIPTION

Also known as RGS16_RAT, Rgs16, Rgsr. Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Plays an important role in the phototransduction cascade by regulating the lifetime and effective concentration of activated transducin alpha. May regulate extra and intracellular mitogenic signals. Interacts with GNAI1 and GNAQ. Interacts with GNAI3, GNAI3 and GNAO1.

EXTERNAL LINKS

uniprot
enzyme classification

Rgs16

Regulator of G-protein signaling 16

Rgs16

Structural Ligandability

Domains Chains

Distribution