FEATURES

FAMILY

DESCRIPTION

Also known as DEF1_HUMAN, DEFA1, DEFA1B, DEF1, DEFA2, MRS. Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. Dimer (PubMed:17452329). Interacts with RETN (PubMed:15064728).

Also known as DEF1_HUMAN, DEFA1, DEFA1B, DEF1, DEFA2, MRS. Defensin 1 and defensin 2 have antibacterial, fungicide and antiviral activities. Has antimicrobial activity against Gram-negative and G ...

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

DEFA1, DEFA1B

Mutations

Mutation(s) distribution

Mutations table