FEATURES

FAMILY

DESCRIPTION

Also known as SCX7_MESMA, SCX7. Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. This toxin is active on both mammals and insects. It can be considered as a cardiotoxin, as it can bind to human cardiac sodium channel and modify its normal properties.

EXTERNAL LINKS

uniprot
enzyme classification

SCX7

Alpha-like toxin BmK-M7

SCX7

Molecular Synopsis