FEATURES

FAMILY

DESCRIPTION

Also known as ACTS_RABIT, ACTA1, ACTA. Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others. Interacts with alpha-actinin (PubMed:8449927). Identified in a complex composed of ACTA1, COBL, GSN AND TMSB4X (PubMed:23009842). Interacts with TTID (By similarity). Interacts (via its C-terminus) with USP25 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification

ACTA1

Structural Ligandability

Domains Chains

Distribution