FEATURES

FAMILY

DESCRIPTION

Also known as HBB_HUMAN, HBB. Involved in oxygen transport from the lung to the various peripheral tissues., LVV-hemorphin-7 potentiates the activity of bradykinin, causing a decrease in blood pressure., functions as an endogenous inhibitor of enkephalin-degrading enzymes such as DPP3, and as a selective antagonist of the P2RX3 receptor which is involved in pain signaling, these properties implicate it as a regulator of pain and inflammation. Heterotetramer of two alpha chains and two beta chains in adult hemoglobin A (HbA). Heterotetramer of two zeta chains and two beta chains in hemoglobin Portland-2, detected in fetuses and neonates with homozygous alpha-thalassemia.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

HBB

Hemoglobin subunit beta

HBB

Molecular Synopsis