FEATURES

FAMILY

DESCRIPTION

Also known as YCGR_ECOLI, ycgR. Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner. When bound to c-di-GMP it binds to elements of the flagellar motor (MotA (PubMed:20303158) and/or FliG and FliM (PubMed:20346719), binding to FliM also occurs in the absence of c-di-GMP), causing the motor to slow down. Thus, increasing levels of c-di-GMP lead to decreased motility. Probably binds 1 c-di-GMP dimer per subunit. Monomer (Probable). Interacts with MotA in the flagellar basal bodies (PubMed:20303158). In another study (PubMed:20346719) it was not seen to interact with MotA, but instead with FliM and FliG, also in the flagellar basal body.

EXTERNAL LINKS

ycgR

Structural Ligandability

Domains Chains

Distribution