FEATURES

FAMILY

DESCRIPTION

Also known as 5DNU_ECOLI, yfbR. Essential component of the deoxycytidine triphosphate (dCTP) pathway for de novo synthesis of thymidylate. Catalyzes the strictly specific dephosphorylation of 2'-deoxyribonucleoside 5'-monophosphates (dAMP, dGMP, dTMP, dUMP, dIMP and dCMP) and does not dephosphorylate 5'-ribonucleotides or ribonucleoside 3'-monophosphates. Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

yfbR

5'-deoxynucleotidase YfbR

yfbR

Molecular Synopsis