FEATURES

FAMILY

DESCRIPTION

Also known as RAE1L_HUMAN, RAE1, MRNP41. Plays a role in mitotic bipolar spindle formation (PubMed:17172455). Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Interacts with NUMA1 (via N-terminal end of the coiled-coil domain); this interaction promotes spindle formation in mitosis (PubMed:17172455). Interacts with NUP98 (PubMed:20498086). Interacts with MYCBP2 (PubMed:22357847). Interacts with USP11 (PubMed:29293652).

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RAE1

Mutations

Mutation(s) distribution

Mutations table