FEATURES

FAMILY

DESCRIPTION

Also known as GSTP1_PIG, GSTP1. Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Involved in the formation of glutathione conjugates of both prostaglandin A2 (PGA2) and prostaglandin J2 (PGJ2). Participates in the formation of novel hepoxilin regioisomers. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration. Homodimer. Interacts with CDK5 (By similarity).

EXTERNAL LINKS

uniprot
enzyme classification

GSTP1

Glutathione S-transferase P

Mutations

Mutation(s) distribution

Mutations table

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