FEATURES

FAMILY

DESCRIPTION

Also known as ML1_VISAL, ML1. The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4, 324 of 28S rRNA. The B chain binds to cell receptors and probably facilitates the entry into the cell of the A chain; B chains are also responsible for cell agglutination (lectin activity). Inhibits growth of the human tumor cell line Molt4. Disulfide-linked dimer of A and B chains.

EXTERNAL LINKS

uniprot
enzyme classification

ML1

Beta-galactoside-specific lectin 1

ML1

Molecular Synopsis