FEATURES

FAMILY

DESCRIPTION

Also known as LIPP_FELCA, PNLIP. Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones. Forms a 1:1 stoichiometric complex with (pro)colipase/CLPS.

EXTERNAL LINKS

uniprot
enzyme classification

PNLIP

Pancreatic triacylglycerol lipase

PNLIP

Structural Ligandability

Domains Chains

Distribution