FEATURES

FAMILY

DESCRIPTION

Also known as DRS2_PHYDS, DRS2. Has antibacterial activity against the Gram-positive bacteria S.aureus and E.faecalis, and the Gram-negative bacteria P.aeruginosa and E.coli. Has antiprotozoal activity against T.cruzi. Has antifungal activity against the yeasts C.tropicalis (MIC=10.9 uM), C.guilliermondii (MIC=21.8 uM), C.albicans (MIC=21.8 uM) and C.albicans ATCC 1023 (MIC=10.9 uM). Decreases viability of murine peritoneal cells. Fuses to, and disrupts liposomes.

EXTERNAL LINKS

uniprot
enzyme classification

DRS2

Dermaseptin-DI2

DRS2

Structural Ligandability

Domains Chains

Distribution