No data available

FEATURES

FAMILY

DESCRIPTION

Also known as TX1_THEBL, TX1. Blocks Kv4.2/KCND2 voltage-gated potassium channels (IC(50) is 193.0 nM) by shifting the voltage-dependence of channel activation to more depolarized potentials. The toxin is thought to bind to the S3-S4 linker region of the voltage sensor domain. Monomer.

Also known as TX1_THEBL, TX1. Blocks Kv4.2/KCND2 voltage-gated potassium channels (IC(50) is 193.0 nM) by shifting the voltage-dependence of channel activation to more depolarized potentials. The tox ...

EXTERNAL LINKS

uniprot
enzyme classification

TX1

Kappa-theraphotoxin-Tb1a

Molecular Synopsis

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