FEATURES

FAMILY

DESCRIPTION

Also known as RHOG_HUMAN, RHOG, ARHG. Required for the formation of membrane ruffles during macropinocytosis. Plays a role in cell migration and is required for the formation of cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB and ARHGEF26/SGEF, which induces cytoskeleton rearrangements and promotes bacterial entry. Interacts with ARHGEF26. Interacts with ARHGEF16.

EXTERNAL LINKS

uniprot
enzyme classification
PhosphoSitePlus

RHOG

Rho-related GTP-binding protein RhoG

RHOG

Molecular Synopsis