FEATURES

FAMILY

DESCRIPTION

Also known as DPO4_SACSO, dbh. Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis. Monomer.

EXTERNAL LINKS

uniprot
enzyme classification

dbh

DNA polymerase IV

dbh

Molecular Synopsis