FEATURES

FAMILY

DESCRIPTION

Also known as RUVA_MYCTU, ruvA. The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. Forms a complex with RuvB.

EXTERNAL LINKS

uniprot
enzyme classification

ruvA

Holliday junction ATP-dependent DNA helicase RuvA

Structural Ligandability

Domains Chains

0 chains assessed

ruvA

Structural Ligandability

Domains Chains

Distribution