FEATURES

FAMILY

DESCRIPTION

Also known as LIPA_MYCTU, lipA. Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. Forms a complex with GcvH, the H protein of the glycine cleavage system. The strength of association is dependent on the presence of S-adenosyl-L-methionine.

EXTERNAL LINKS

uniprot
enzyme classification

lipA

Mutations

Mutation(s) distribution

Mutations table