FEATURES

DESCRIPTION

Also known as HTMR_MYCTU, MTCY274.18. Represses expression of the HQNO methyltransferase htm gene (Rv0560c) by binding to its promoter region (PubMed:26303802, PubMed:27432954, PubMed:28743871). Also represses the expression of at least five other genes, including the methyltransferase Rv0558 (PubMed:26303802). Binds salicylate (SA), para-aminosalicylic acid (PAS) and gemfibrozil (PubMed:28743871). Homodimer.

EXTERNAL LINKS

uniprot
enzyme classification

MTCY274.18

HTH-type transcriptional repressor Rv2887

MTCY274.18

Molecular Synopsis