FEATURES

FAMILY

DESCRIPTION

Also known as CLPP2_MYCTU, clpP2. Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). Degrades anti-sigma-D factor RsdA when present in a complex with ClpP1 and ClpX. Degrades anti-sigma-E factor RseA in the presence of ClpC1. Does not seem to act on anti-sigma-L factor RslA. Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes (By similarity). Forms a complex with ClpP1 and ClpX.

EXTERNAL LINKS

uniprot
enzyme classification

clpP2

ATP-dependent Clp protease proteolytic subunit 2

clpP2

Molecular Synopsis