FEATURES

FAMILY

class-III pyridoxal-phosphate-dependent aminotransferase family

DESCRIPTION

Also known as BIOA_MYCTU, bioA. Catalyzes the reversible transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7, 8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor (PubMed:20565114, PubMed:16984394). Can also use sinefungin but not S-adenosylhomocysteine as substrate (PubMed:20565114). Homotetramer (PubMed:16984394). Homodimer (PubMed:20565114).

EXTERNAL LINKS

uniprot
enzyme classification

bioA

Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Mutations

Mutation(s) distribution

Mutations table

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