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FEATURES

FAMILY

alpha-IPM synthase/homocitrate synthase family

DESCRIPTION

Also known as LEU1_MYCTU, leuA. Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate). Homotetramer.

Also known as LEU1_MYCTU, leuA. Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropy ...

EXTERNAL LINKS

uniprot
enzyme classification

leuA

2-isopropylmalate synthase

Mutations

Mutation(s) distribution

Mutations table

Search Mutation

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