FEATURES

FAMILY

DESCRIPTION

Also known as ACCD6_MYCTU, accD6. Component of a biotin-dependent acyl-CoA carboxylase complex. This subunit transfers the CO2 from carboxybiotin to the CoA ester substrate (PubMed:17114269). When associated with the alpha3 subunit AccA3, is involved in the carboxylation of acetyl-CoA and propionyl-CoA, with a preference for acetyl-CoA (PubMed:17114269). Homodimer (PubMed:25092705). The biotin-dependent acyl-CoA carboxylase complex is composed of AccA3, which contains the biotin carboxylase (BC) and biotin carboxyl carrier protein (BCCP) domains, and AccD6, which contains the carboxyl transferase (CT) domain (PubMed:17114269). The AccA3/AccD6 complex forms a dodecamer (PubMed:17114269).

EXTERNAL LINKS

accD6

Biotin-dependent acetyl-/propionyl-coenzyme A carboxylase beta6 subunit

Mutations

Mutation(s) distribution

Mutations table

Search Mutation