FEATURES

DESCRIPTION

Also known as HETS_PODAS, het-s, small s. Responsible for heterokaryon incompatibility, a process that ensures that during spontaneous, vegetative cell fusion only compatible cells from the same colony survive (non-self-recognition). Forms a prion for the non-Mendelian trait [het-s]. Interacts with het-S from incompatible cells to trigger a lethal reaction that prevents the formation of viable heterokaryons. It is unknown if the native, soluble protein has a cellular function. Homodimer. Forms heterodimers with het-S.

EXTERNAL LINKS

uniprot
enzyme classification

het-s

Heterokaryon incompatibility protein s

het-s

Molecular Synopsis