FEATURES

FAMILY

DESCRIPTION

Also known as THII_STRP2, thiI. Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.

EXTERNAL LINKS

uniprot
enzyme classification

thiI

Probable tRNA sulfurtransferase

thiI

Molecular Synopsis