FEATURES

FAMILY

DESCRIPTION

Also known as LYSB_BPML5, 12. Endolysin that degrades the junction between mycolic acid and peptidoglycans in the host cell wall and participates with the holin protein in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the mycolic acid-rich outer membrane. Cleaves the ester linkage joining the mycolic acid-rich outer membrane to arabinogalactan, releasing free mycolic acids.

EXTERNAL LINKS

uniprot
enzyme classification

12

Endolysin B

12

Structural Ligandability

Domains Chains

Distribution